- F -
F(ab')2
A fragment of an antibody containing two antigen-binding sites generated by cleavage of the antibody molecule with the enzyme pepsin which cuts at the hinge region C-terminally to the inter-H-chain disulphide bond.
Fab
Fragment of antibody containing the antigen-binding site, generated by cleavage of the antibody with the enzyme papain, which cuts at the hinge region N-terminally to the inter-H-chain disulphide bond and generates two Fab fragments from one antibody molecule.
Fc
Fragment of antibody without antigen-binding sites, generated by cleavage with papain; the Fc fragment contains the C-terminal domains of the heavy immunoglobulin chains.
Fc receptor (FcR)
A receptor on a cell surface with specific binding affinity for the Fc portion of an antibody molecule. Fc receptors are found on many types of cells.
Fluorescent antibody
An antibody coupled with a fluorescent dye, used with a fluorescence microscope to detect antigen on cells, tissues, or microorganisms.
Freund's complete adjuvant
A water-in-oil emulsion that contains an immunogen, an emulsifying agent, and killed mycobacteria which enhance the immune response to the immunogen; termed "incomplete" Freund's adjuvant if mycobacteria are not included.
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