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Second set rejection
Accelerated rejection of an allograft in an already immune recipient.
Secondary lymphoid organs
Organs in which antigen-driven proliferation and differentiation of B and T lymphocytes takes place.
Secretory component
A surface receptor on epithelial cells lining mucosal surfaces which binds dimeric IgA and transports it through the cell into mucosal secretions.
Serum sickness
A hypersensitivity reaction consisting of fever, rashes, joint pain and glomerulonephritis, resulting from localization of circulating, soluble, antigen-antibody complexes, which induce inflammatory reactions. Serum sickness was originally induced following therapy with large doses of antibody from a foreign source - e.g. horse serum.
Slow-reacting substance of anaphylaxis (SRS-A)
A group of leukotrienes released by mast cells during anaphylaxis which induces a prolonged constriction of smooth muscle. This prolonged constriction is not reversible by treatment with antihistamines.
Suppression
A mechanism for producing a specific state of immunologic unresponsiveness by the induction of suppressor T cells. This type of unresponsiveness is passively transferable by suppressor T cells or their soluble products.
Syngeneic
Literally, genetically identical.
Syngraft
Same as isograft.
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